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2 edition of Pharmacological properties of dehydroascorbic acid and ascorbic acid found in the catalog.

Pharmacological properties of dehydroascorbic acid and ascorbic acid

Sven Erik Sjostrand

Pharmacological properties of dehydroascorbic acid and ascorbic acid

effects on the central and peripheral nervous systems in experimental animals.

by Sven Erik Sjostrand

  • 145 Want to read
  • 34 Currently reading

Published in Stockholm .
Written in English


Edition Notes

Bibliography, p. 74-79.

SeriesActa physiologica Scandinavica -- Supplementum, 356
The Physical Object
Pagination79 p. :
Number of Pages79
ID Numbers
Open LibraryOL17246437M

of this change is a stronger acid than dehydroascorbic acid, and is a more powerful reducing agent than ascorbic acid itself. It is distinguished from dehydroascorbic acid also in that it is not reduced by H&3 in acid solution, nor by glutathione in neutral or alkaline Size: 2MB. Ascorbic acid and dehydroascorbic acid are commonly used biomarkers of oxidative stress in a variety of experimental models. However, the accurate measurement of these labile compounds remains a challenge both in terms of sample collection and analysis. Determination of dehydroascorbic acid most commonly involves indirect by:

Abstract Background The importance of consumption of vitamin C (ascorbic acid) for human health is well known, as adequate availability of vitamin C is necessary for proper immune functioning, suppression of virus replication, suppression of inflammation, and in the process of healing in many chronic diseases. Ascorbic Acid and Dehydroascorbic Acid Concentrations in Plasma and Peripheral Blood Mononuclear Cells after Oral Liposomal-Encapsulated or Intravenous Ascorbic Acid Delivery. J Orthomol Med, 32(4). _____ Abstract Background The importance of consumption of vitamin C (ascorbic acid) for human health is well known, as adequateFile Size: KB.

  ABSTRACT. Using a reliable, newly developed assay for ascorbic acid (reduced form) and dehydroascorbic acid (DHAA; the oxidized form) in plasma, we studied the influence of age, sex, and smoking on healthy, age-stratified, and randomly selected Cited by: View and buy high quality L-Dehydroascorbic acid from Tocris Bioscience. GLUT1 substrate; oxidized form of L-Ascorbic ry: Glucose Transporters.


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Pharmacological properties of dehydroascorbic acid and ascorbic acid by Sven Erik Sjostrand Download PDF EPUB FB2

Acta Physiol Scand Suppl. ; Pharmacological properties of dehydroascorbic acid and ascorbic acid. Effects on the central and peripheral nervous systems in experimental by: Get this from a library. Pharmacological properties of dehydroascorbic acid and ascorbic acid.

Effects on the central and peripheral nervous systems in experimental animals. [Sven Erik Sjöstrand]. Dehydroascorbic acid (DHA) is an oxidized form of ascorbic acid (vitamin C). It is actively imported into the endoplasmic reticulum of cells via glucose transporters.

It is trapped therein by reduction back to ascorbate by glutathione and other thiols. The (free) chemical radical semidehydroascorbic acid (SDA) also belongs to the group of oxidized ascorbic Number: Dehydroascorbic acid is made from the oxidation of ascorbic reaction is reversible, but dehydroascorbic acid can instead undergo irreversible hydrolysis to 2,3-diketogulonic oascorbic acid as well as ascorbic acid are both termed Vitamin C, but the latter is the main form found in the body, both dehydroascorbic acid and ascorbic acid have similar biological.

Ascorbic acid | HC6H7O6 or C6H8O6 | CID - structure, chemical names, physical and chemical properties, classification, patents, literature, biological.

M.A. Kall, in Encyclopedia of Food Sciences and Nutrition (Second Edition), Determination of vitamin C as total ascorbic acid.

Dehydroascorbic acid is reduced to AA at neutral pH in the presence of thiol-containing reducing agents such as cysteine, homocysteine, 2-mercaptoethanol, and DTT.

During incubation of the sample extract with a reductant, DHAA should be transformed quantitatively. Ascorbic acid (AsA) and its first oxidation product dehydroascorbic acid (which can be reduced in the human body) might be considered as vitamin C.

AsA is a water soluble carbohydrate-derived compound showing antioxidant and acidic properties due to the presence of a 2,3-enediol moiety (Figure ).

Advantages and limitations of commonly used and recently developed methods for the analysis of ascorbic acid and dehydroascorbic acid in foods and biological samples have been reviewed. Various procedures based on titrimetric, spectrophotometric, or fluorometric principles have been used for this purpose.

Depending upon the procedure selected, dehydroascorbic acid, hydroascorbic acid, or total. Ascorbic acid (vitamin c) is reversibly oxidized to dehydroascorbic acid (vitamin c) in the body. These two forms of the vitamin are believed to be important in oxidation-reduction reactions.

The vitamin is involved in tyrosine metabolism, conversion of folic acid to folinic acid, carbohydrate metabolism, synthesis of lipids and proteins.

Simultaneous analysis of ascorbic acid and dehydroascorbic acid in fruit and vegetables by high-performance liquid chromatography. Journal of Chromatography A, DOI: /S(01)Cited by:   Oxidation of Ascorbic Acid to Dehydroascorbic Acid.

By DONALD W. BOLIN, LUCILLE BOOK. See all Hide authors and affiliations. Science 07 Nov Vol. Issuepp. DOI: /science Article; Info & Metrics; eLetters; PDF; This Cited by: ; Native ascorbate oxidase from Cucurbita species.

Catalyzes the oxidation of ascorbioxidation of ascorbic acid to dehydroascorbic acid. Suitable for eliminating interference of ascorbic acid in clinical assays and for determination of ascorbic acid.

Proper use of ascorbic acid Dosing. The dose of ascorbic acid will be different for different patients. Follow your doctor's orders or the directions on the label.

The following information includes only the average doses of ascorbic acid. If your dose is different, do not change it / (L)-Dehydroascorbic acid CAS Number Empirical Formula (Hill Notation) C 6 H 6 O 6.

Molecular Weight EC Number MDL number MFCD PubChem Substance ID NACRES NA   Science 29 Aug Vol. Issuepp. DOI: /scienceCited by: 3. Using a novel high performance liquid chromatography (HPLC) determination of ascorbic acid and dehydroascorbic acid, we have measured the relative amounts of ascorbate and dehydroascorbate in 20 normal controls and in paired sera and synovial fluid from 13 patients with rheumatoid arthritis (RA).

In complete contrast to previous published Cited by: Summary This chapter contains sections titled: Physical and Chemical Properties of Ascorbic Acid Methods Based upon Reduction of 2,6‐Dichlorophenolindophenol Dinitrophenylhydrazine Methods Chemical Determination of Ascorbic, Dehydroascorbic, and Diketogulonic Acids - Roe - - Methods of Biochemical Analysis - Wiley Online LibraryCited by:   Ascorbic acid and dehydroascorbic acid were determined by using HPLC with coulometric electrochemical detection, and protein binding was determined by centrifugal ultrafiltration.

Ascorbic acid was free in plasma and serum of normal, healthy volunteers, 10 men and 10 women. Ascorbic acid was detectable only in its reduced by: of ascor bic acid at in fluenz a infecti on // Russian Journ al of Infect ion and Immuni ty = Infek tsi ya i immunite t,vol.

7, no. 4, pp. 3 19– doi: 1 0. 89/ 76 17 Vitamin C is a general term for compounds having ascorbic acid activity, including ascorbic acid, dehydroascorbic acid, and its isomers. A few hundred years ago, researchers found that scurvy.

DE | Dehydroascorbic Acid, an oxidized form of ascorbic acid, can be used as a vitamin C dietary supplement. Ungraded products supplied by Spectrum are indicative of a grade suitable for general industrial use or research purposes and typical.Abstract Ascorbic acid (vitamin C) is extensively used in a variety of formulations including creams.

It is an ingredient of anti-aging cosmetic products alone or along with alpha-tocopherol (vitamin E). In solutions and creams, ascorbic acid is susceptible to air and .Chemical properties Acidity. Ascorbic acid is a vinylogous carboxylic acid and forms the ascorbate anion when deprotonated on one of the hydroxyls.

This property is characteristic of reductones: enediols with a carbonyl group adjacent to the enediol group, namely with the group –C(OH)=C(OH)–C(=O)–.

The ascorbate anion is stabilized by electron delocalization that results from resonance E number: E (antioxidants, ).